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Although primary BAs are elevated in the stool of both IBS-C and IBS-D patients (Mars et al., 2020), secondary BAs are reduced in the latter group ( de novo synthesis (Mars et al., 2020)

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This may be more appropriate than taking multiple drugs to lower cholesterol

Initial results can be seen 6 weeks of daily use of Cyspera/ cysteamine pigmentation cream for 15 minutes to the areas of hyperpigmentation